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Overall, the results of these three studies suggest that antidepressant medications are associated with symptomatic improvement among potentially prodromal adolescents and young adults.
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In support of such hypothesis comes the demonstration that depressed patients show a reduction of monoamine turnover with low levels of monoamines and metabolites in cerebrospinal fluid, plasma and urine, notwithstanding the variability and methodological differences which have produced contrasting results.
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Second, the aim of the present meta-analysis was to test whether weight changes are significantly different from the null for each AP across the 4 exposure periods.
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